Aldosterone, Normotension, and Diastolic Dysfunction
نویسندگان
چکیده
منابع مشابه
[Diastolic dysfunction and diastolic heart failure].
There are frequent clinical Cases in Cardiological practice when cardiac failure develops together with normal systolic function of left ventricle. In these patients after revealing the diastolic dysfunction the heart diastolic failure is diagnosed, but in frequent cases this diagnosis is based on exclusion method. According to Framingham data the number of patients with clinically manifested d...
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Heart failure with preserved left ventricular (LV) ejection fraction is commonly viewed as the consequence of diastolic dysfunction. Hypertension is the most common cause for the development of diastolic dysfunction and LV hypertrophy leading to symptomatic hypertensive heart disease. Strict blood pressure control therefore is mandatory to prevent diastolic heart failure in patients with hypert...
متن کاملDiastolic dysfunction.
Diastolic dysfunction of the heart is characterized by normal left ventricular contractility and normal ejection fraction, however ventricular relaxation is impaired. In systolic dysfunction, ventricular contractility and ejection fraction are reduced, in addition to impaired relaxation. The prevalence of diastolic dysfunction is increased in the elderly, especially those who have had inadequat...
متن کاملEffect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure.
BACKGROUND Specific treatments targeting the pathophysiology of hypertensive heart disease are lacking. As aldosterone has been implicated in the genesis of myocardial fibrosis, hypertrophy, and dysfunction, we sought to determine the effects of aldosterone antagonism on myocardial function in hypertensive patients with suspected diastolic heart failure by using sensitive quantitative echocardi...
متن کاملEarly diastolic filling dynamics in diastolic dysfunction
BACKGROUND The aim of the study was to determine the relationship between the rate of peak early mitral inflow velocity and the peak early diastolic mitral annular tissue velocities in normal controls and to compare them with subjects with diastolic dysfunction. METHODS The relationship between early passive diastolic transmitral flow and peak early mitral annular velocity in the normal and i...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2005
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2005-1613